I haven't tried any USB card but I am sure they will significantly improve the sound. It's always about synergy though. I am quite familiar with JCAT as I had their Signature USB cable and it's by far the best USB cable I tried. So if I relate their USB cables to JCAT other offerings I am sure that USB card would do wonders. You will have more success in your search over the JCAT forums as plenty of folks there build their own media streamers. You could also contact Marcin directly thru their website.
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