Not quite apples to apples but I am driving the Sopra No. 3's with a Reference 150 in a medium size room (14'x24'). I would imagine the Reference 75SE would also do well because the power difference isn't that huge, but as others have said, you should do your own audition if at all possible. Also keep in mind that the sense of loudness you get from an amplifier doesn't always correlate 100% with the rated power. My Reference 150 can play significantly "louder" than other amps with similar power.
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