I have Guarneri Memento's in a 13x21x10 room. They fill the space beautifully. Granted they are just 2-way speakers, but they hit above their weight class IMO.
I have heard the Amati Futura in a large listening room and it also did a great job. I think a lot of having the speakers fit the space is to ensure you have them placed properly and do what you can to minimize the room effects (via treatments).
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